منابع مشابه
Broad-spectrum antiviral agents
Development of highly effective, broad-spectrum antiviral agents is the major objective shared by the fields of virology and pharmaceutics. Antiviral drug development has focused on targeting viral entry and replication, as well as modulating cellular defense system. High throughput screening of molecules, genetic engineering of peptides, and functional screening of agents have identified promi...
متن کاملAntiviral Replication Agents
The last few decades have shown a great progress in the development of antiviral agents that were licensed for treatment of Human immunodeficiency virus (HIV), herpesviruses, hepatitis viruses and respiratory viruses. The majority of viral infections clear spontaneously and are not in need for specific medical therapy. However, antiviral chemotherapy is indicated in certain clinical situations ...
متن کاملVaccines and Antiviral Agents
A vaccine is a biological preparation that improves immunity to a particular disease. A vac‐ cine typically contains an agent that resembles a disease-causing microorganism, and is of‐ ten made from weakened or killed forms of the microbe, its toxins or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so...
متن کاملMolecular Targets for Antiviral Agents
There are a number of virus-specific processes within the virus replicative cycle or virus-infected cell that have proven to be attractive targets for chemotherapeutic intervention, i.e., virus adsorption and entry into the cells, reverse (RNA 3 DNA) transcription, viral DNA polymerization, and cellular enzymatic reactions that are associated with viral DNA and RNA synthesis and viral mRNA matu...
متن کاملProtease inhibitors as antiviral agents.
Currently, there are a number of approved antiviral agents for use in the treatment of viral infections. However, many instances exist in which the use of a second antiviral agent would be beneficial because it would allow the option of either an alternative or a combination therapeutic approach. Accordingly, virus-encoded proteases have emerged as new targets for antiviral intervention. Molecu...
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ژورنال
عنوان ژورنال: Medical Clinics of North America
سال: 1988
ISSN: 0025-7125
DOI: 10.1016/s0025-7125(16)30766-0